Amorepacific Uses AI to Develop Hair-Strengthening Peptide

Amorepacific has developed a new peptide designed to strengthen hair keratin using artificial intelligence and molecular modeling technology. The ingredient targets damage within the hair shaft, where weakened keratin structures can lead to breakage and reduced resilience.

The company’s research reflects its broader focus on AI-driven beauty innovation and long-term hair and skin health.

Targeting hair damage at the molecular level

Amorepacific’s R&I Center used molecular docking and molecular dynamics simulations to study potential peptide candidates. Through this process, researchers identified Tripeptide-132 as the strongest option because of its ability to bind effectively to hair keratin.

The research focuses on reinforcing damaged keratin structures inside the hair. By strengthening this internal framework, the peptide aims to improve resilience and reduce breakage caused by everyday styling, drying, and environmental stress.

Improving strength, smoothness, and breakage resistance

Experimental results showed that hair treated with Tripeptide-132 had up to a 44% increase in tensile strength and a 50% reduction in breakage. Analysis of the hair cuticle also showed improvements in surface alignment and smoothness.

These findings suggest that the peptide supports both internal repair and visible hair quality. It helps explain how molecular-level bonding can contribute to stronger, softer, and shinier hair.

From research to finished products

Amorepacific has already applied the peptide technology to finished haircare products. The ingredient is included in COSRX’s recently launched Peptide-132 Shampoo, Treatment, and Hair Bonding Oil.

By moving the discovery into consumer products, the company is connecting AI-based research with practical haircare solutions. This approach highlights how advanced modeling tools can help brands develop more targeted and effective ingredients.